2. Anti-infection
  3. HBV
  4. Daplusiran sodium

Daplusiran sodium is a siRNA in JNJ-3989 (JNJ-73763989). JNJ-3989 is comprised of 2 siRNAs (Daplusiran and Tomligisiran), that target hepatitis B virus (HBV) mRNAs for degradation, thereby inhibiting HBV replication.

For research use only. We do not sell to patients.

Gene Regulation Tool

RNA, (Am-sp-(2'-deoxy-2'-fluoro)G-sp-Am-sp-(2'-deoxy-2'-fluoro)A-Am-(2'-deoxy-2'-fluoro)A-Um-(2'-deoxy-2'-fluoro)U-Gm-(2'-deoxy-2'-fluoro)A-Gm-(2'-deoxy-2'-fluoro)A-Gm-(2'-deoxy-2'-fluoro)A-Am-(2'-deoxy-2'-fluoro)G-Um-(2'-deoxy-2'-fluoro)C-Cm-Am-sp-Cm), complex with RNA ([1'-de(6-amino-9H-purin-9-yl)]dA-(5'→5')-sp-Gm-Um-Gm-Gm-Am-Cm-Um-Um-(2'-deoxy-2'-fluoro)C-(2'-deoxy-2'-fluoro)U-(2'-deoxy-2'-fluoro)C-Um-Cm-Am-Am-Um-Um-Um-Um-Cm-Um-(3'→3')-sp-[1'-de(6-amino-9H-purin-9-yl)]dA) 3'-[O-[cis-4-[(3S,8S)-17-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-3,8-bis[[[2-[2-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethyl]amino]carbonyl]-1,6,11-trioxo-15-oxa-2,7,12-triazaheptadec-1-yl]cyclohexyl] hydrogen phosphorothioate] (1:1), sodium salt

Daplusiran sodium Chemical Structure

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Daplusiran sodium Related Antibodies

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Description

Daplusiran sodium is a siRNA in JNJ-3989 (JNJ-73763989). JNJ-3989 is comprised of 2 siRNAs (Daplusiran and Tomligisiran), that target hepatitis B virus (HBV) mRNAs for degradation, thereby inhibiting HBV replication.

Molecular Weight

16558.80

Formula

C492H606F12N163Na440O310P43S7
SMILES

[Daplusiran (sodium)]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Daplusiran sodium Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DaplusiranHBVHepatitis B virusInhibitorinhibitorinhibit

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Daplusiran sodium
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HY-177625A
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