2. GPCR/G Protein Neuronal Signaling Cytoskeleton Immunology/Inflammation NF-κB Metabolic Enzyme/Protease Apoptosis
  3. GPR55 Collagen Reactive Oxygen Species (ROS) Apoptosis
  4. Cyclic peptide P1-1

Cyclic peptide P1-1 is a high-potent GPR55 antagonist. Cyclic peptide P1-1 antagonizes GPR55 and suppresses collagen secretion. Cyclic peptide P1-1 reduces ROS production, attenuates ER stress, and inhibits mitochondria-associated Apoptosis. Cyclic peptide P1-1 inhibits the expression of α-SMA and COL1α. Cyclic peptide P1-1 ameliorates CCl4 (HY-Y0298)-induce and MCD-diet-induce acute liver inflammation and fibrosis.

For research use only. We do not sell to patients.

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Cyclic peptide P1-1

Cyclic peptide P1-1 Chemical Structure

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Cyclic peptide P1-1 Related Antibodies

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Description

Cyclic peptide P1-1 is a high-potent GPR55 antagonist. Cyclic peptide P1-1 antagonizes GPR55 and suppresses collagen secretion. Cyclic peptide P1-1 reduces ROS production, attenuates ER stress, and inhibits mitochondria-associated Apoptosis. Cyclic peptide P1-1 inhibits the expression of α-SMA and COL1α. Cyclic peptide P1-1 ameliorates CCl4 (HY-Y0298)-induce and MCD-diet-induce acute liver inflammation and fibrosis[1].

Molecular Weight

991.19

Formula

C40H70N12O13S2
Sequence

Cys-Lys-Lys-Asn-Ser-Pro-Thr-Ile-Cys (Disulfide bridge: Cys1-Cys9)
Sequence Shortening

CKKNSPTIC (Disulfide bridge: Cys1-Cys9)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Cyclic peptide P1-1 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cyclic peptide P1-1GPR55CollagenReactive Oxygen Species (ROS)ApoptosisG protein-coupled receptor 55Inhibitorinhibitorinhibit

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