2. Membrane Transporter/Ion Channel
  3. NKCC Potassium Channel Sodium Channel
  4. AY 31906

AY 31906 is an orally active pyrimidine sulfonamide diuretic. AY 31906 exhibits potent diuretic and natriuretic activities in rats and dogs, along with relatively potassium-sparing properties. AY 31906 exhibits superior activity to Furosemide (HY-B0135). AY-31906 also has antihypertensive effects and can be used in the research of cardiovascular diseases.

For research use only. We do not sell to patients.

AY 31906

AY 31906 Chemical Structure

CAS No. : 124788-46-1

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Description

AY 31906 is an orally active pyrimidine sulfonamide diuretic. AY 31906 exhibits potent diuretic and natriuretic activities in rats and dogs, along with relatively potassium-sparing properties. AY 31906 exhibits superior activity to Furosemide (HY-B0135). AY-31906 also has antihypertensive effects and can be used in the research of cardiovascular diseases[1][2].

Molecular Weight

368.45

Formula

C15H24N6O3S
CAS No.
SMILES

CC(C)NC(NS(=O)(C1=CN=C(N)N=C1N[C@H]2[C@@]3([H])C[C@@](CC3)([H])C2)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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AY 31906 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AY 31906124788-46-1AY31906AY-31906NKCCPotassium ChannelSodium ChannelNa-K-Cl cotransporterNa(+)-K(+)-Cl(-) cotransporterNa+-K+-Cl− cotransporter KcsANa channelsNa+ channelsDiureticdogratcardiovascular diseasesInhibitorinhibitorinhibit

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