2. GPCR/G Protein
  3. Free Fatty Acid Receptor
  4. AM-6226

AM-6226 is a potent and orally active G protein coupled receptor 40 (GPR40) full agonist with an EC50 of 0.12 μM. AM-6226 can activate the GPR40 receptors on pancreatic β cells and enteroendocrine L cells, promote insulin secretion in a glucose-dependent manner and also increase the release of incretin hormones (GLP-1, GIP), thereby avoiding the risk of hypoglycemia. AM-6226 can be used for the research of metabolic disease, such as diabetes.

For research use only. We do not sell to patients.

AM-6226

AM-6226 Chemical Structure

CAS No. : 1449742-87-3

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AM-6226 Related Antibodies

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Description

AM-6226 is a potent and orally active G protein coupled receptor 40 (GPR40) full agonist with an EC50 of 0.12 μM. AM-6226 can activate the GPR40 receptors on pancreatic β cells and enteroendocrine L cells, promote insulin secretion in a glucose-dependent manner and also increase the release of incretin hormones (GLP-1, GIP), thereby avoiding the risk of hypoglycemia. AM-6226 can be used for the research of metabolic disease, such as diabetes[1].

Molecular Weight

522.62

Formula

C32H36F2O4
CAS No.
SMILES

CC1([C@@H](CCC1)C2=C(C3=CC(OC)=CC=C3F)C=CC(COC4=C(C([C@H](CC)CC(O)=O)=CC=C4)F)=C2)C
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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AM-6226 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AM-62261449742-87-3AM6226AM 6226Free Fatty Acid ReceptorFFARInhibitorinhibitorinhibit

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