2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9980):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W013652S
    N-Tigloylglycine-2,2-d2
    N-Tigloylglycine-2,2-d2 is the deuterium labeled N-Tigloylglycine-2,2.
    N-Tigloylglycine-2,2-d<sub>2</sub>
  • HY-N8593S
    Undecane-d24
    Undecane-d24 is the deuterium labeled Undecane (HY-N8593).Undecane is a potent cAMP agonist with anti-allergic and anti-inflammatory activities. Undecane inhibits degranulation and the secretion of histamine and TNF-α. Undecane reverses the increased levels of p38 phosphorylation, NF-κB transcriptional activity and target cytokine/chemokine genes, including thymus and activation-regulated chemokine (TARC), macrophage-derived chemokine (MDC) and interleukin-8 (IL-8). Undecane can be used for the study of skin inflammatory disorders, such as atopic dermatitis.
    Undecane-d<sub>24</sub>
  • HY-13317S4
    Oseltamivir-d3 hydrochloride
    Oseltamivir-d3 hydrochloride is the deuterium-labeled Oseltamivir (HY-13317). Oseltamivir is an influenza virus neuraminidase inhibitor (NAI). Oseltamivir inhibits influenza A/H3N2, A/H1N2, A/H1N1, and B viruses with mean IC50s of 0.67, 0.9, 1.34 and 13 nM, respectively. Anti-influenza A and B agent.
    Oseltamivir-d<sub>3</sub> hydrochloride
  • HY-Z1430S
    (3R,4S)-Paroxetine-d4 hydrochloride
    Paroxetine EP impurity D-d4 (hydrochloride) is deuterium labeled (3R,4S)-3-((benzo[d][1,3]dioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine (Paroxetine Impurity).
    (3R,4S)-Paroxetine-d<sub>4</sub> hydrochloride
  • HY-W707528
    Propofol-d14
    Propofol-d14 (2,6-Diisopropylphenol-d14) is the deuterium labeled Propofol (HY-B0649). Propofol potently and directly activates GABAA receptor and inhibits glutamate receptor mediated excitatory synaptic transmission. Propofol has antinociceptive properties and is used for sedation and hypnotic.
    Propofol-d<sub>14</sub>
  • HY-146838S
    17:0-18:1 PC-d5
    17:0-18:1 PC-d5 is deuterium labeled 17:0-18:1 PC.
    17:0-18:1 PC-d<sub>5</sub>
  • HY-138199S1
    Omeprazole sulfone N-oxide-d3
    Omeprazole sulfone N-oxide-d3 is the deuterium labeled Omeprazole sulfone N-Oxide.
    Omeprazole sulfone N-oxide-d<sub>3</sub>
  • HY-W283336S
    2,5-Di-(tert-butyl)-4-methoxyphenol-3,6-d20
    2,5-Di-(tert-butyl)-4-methoxyphenol-3,6-d20 is the deuterium labeled 2,5-Di-tert-butyl-4-methoxyphenol.
    2,5-Di-(tert-butyl)-4-methoxyphenol-3,6-d<sub>20</sub>
  • HY-142651S
    Prochlorperazine-d3 mesylate
    Prochlorperazine-d3 (mesylate) is the deuterium labeled Prochlorperazine mesylate.
    Prochlorperazine-d<sub>3</sub> mesylate
  • HY-13749S2
    Sitagliptin-d4
    Sitagliptin-d4 (MK-0431-d4) is deuterium labeled Sitagliptin (HY-13749). Sitagliptin is an orally active and highly selective DPP4 inhibitor with an IC50 value of 19 nM. Sitagliptin blocks the degradation of glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP) by competing inhibition mechanism (Kᵢ = 1 nM), thereby increasing the level of active incretin. Sitagliptin can also directly stimulate the secretion of GLP-1 by intestinal L cells by activating the cAMP/PKA and ERK1/2 pathways, and this effect is independent of DPP-4. Sitagliptin shows protective effects on pancreatic islet grafts in 1-type diabetes models. Sitagliptin can be used for the study of 1-type and 2-type diabetes.
    Sitagliptin-d<sub>4</sub>
  • HY-107494S3
    13-cis-4-Oxoretinoic acid-d6
    13-cis-4-Oxoretinoic acid-d6 (4-Keto 13-cis-retinoic acid-d6; 4-Oxoisotretinoin-d6; Ro 22-6595-d6) is the deuterium labeled 13-cis-4-Oxoretinoic acid (HY-107494). 13-cis-4-Oxoretinoic acid (4-Keto 13-cis-retinoic acid) is a metabolite of vitamin A in human plasma.
    13-cis-4-Oxoretinoic acid-d<sub>6</sub>
  • HY-W700259
    4-(4-Aminophenoxy)-N-methylpicolinamide-d3
    4-(4-Aminophenoxy)-N-methylpicolinamide-d3 (4-(4-aminophenoxy)-N-methylpyridine-2-carboxamide-d3) is the deuterium labeled 4-(4-Aminophenoxy)-N-methylpicolinamide (HY-78034).
    4-(4-Aminophenoxy)-N-methylpicolinamide-d3
  • HY-W758392
    (±)-Ipratropium-d3 Bromide (N-methyl-d3)
    (±)-Ipratropium-d3 Bromide (N-methyl-d3) is the deuterium labeled (±)-Ipratropium Bromide.
    (±)-Ipratropium-d3 Bromide (N-methyl-d<sub>3</sub>)
  • HY-W131180S
    2,3,5,6-Tetrachloroaniline-d3
    2,3,5,6-Tetrachloroaniline-d3 is the deuterium labeled 2,3,5,6-Tetrachloroaniline.
    2,3,5,6-Tetrachloroaniline-d<sub>3</sub>
  • HY-I0400S2
    N-Acetylneuraminic acid-13C-2
    N-Acetylneuraminic acid-13C-2 is the 13C labeled N-Acetylneuraminic acid.
    N-Acetylneuraminic acid-<sup>13</sup>C-2
  • HY-W723995
    Ethyl-2,2,2-d3 acetate
    Ethyl-2,2,2-d3 acetate is the deuterium labeled Ethyl acetate.
    Ethyl-2,2,2-d<sub>3</sub> acetate
  • HY-17358S1
    Loteprednol Etabonate-d3
    Loteprednol Etabonate-d3 is the deuterium labeled Loteprednol Etabonate. Loteprednol etabonate (LE) is an orally active "soft" steroid belonging to a unique class of glucocorticoids. Loteprednol etabonate (LE) exhibits anti-inflammatory activity and has been used in optometry and ophthalmology.
    Loteprednol Etabonate-d<sub>3</sub>
  • HY-10582S2
    Flurbiprofen-13C,d3
    Flurbiprofen-13C,d3 is the 13C- and deuterium labeled Flurbiprofen. Flurbiprofen (dl-Flurbiprofen) is a potent, orally active nonsteroidal anti-inflammatory agent (NSAIA/NSAID), with antipyretic and analgesic activities. Flurbiprofen is commonly used for the research of inflammatory diseases, including osteoarthritis and rheumatoid arthritis. Flurbiprofen is a non-selective cyclooxygenase (COX) inhibitor that can be used for the research of colorectal cancer.
    Flurbiprofen-<sup>13</sup>C,d<sub>3</sub>
  • HY-N1150S6
    Thymidine-d2
    Thymidine-d2 is the deuterium labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[1
    Thymidine-d<sub>2</sub>
  • HY-B1395S1
    Mecamylamine hydrochloride-13C4,15N
    Mecamylamine (hydrochloride)-13C4,15N is the 13C-labeled and 15N-labeled Mecamylamine hydrochloride. Mecamylamine hydrochloride is an orally active, nonselective, noncompetitive nAChR antagonist that can treat various neuropsychiatric disorders. Mecamylamine hydrochloride is originally used as a ganglionic blocker in treating hypertension. Mecamylamine hydrochloride can easily crosses the blood-brain barrier.
    Mecamylamine hydrochloride-<sup>13</sup>C<sub>4</sub>,<sup>15</sup>N