Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (4)

Isotope-Labeled Compounds Related Products (9980):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-D0184S5

2'-Deoxycytidine-¹³C₉
2'-Deoxycytidine-¹³C₉ (Deoxycytidine-¹³C₉; Cytosine deoxyriboside-¹³C₉; Deoxyribose cytidine-¹³C₉) is ¹³C-labeled 2'-Deoxycytidine (HY-D0184). 2'-Deoxycytidine, a deoxyribonucleoside, could inhibit biological effects of Bromodeoxyuridine (Brdu).

HY-Y1004S4

1-Decanol-d₄
1-Decanol-d₄ is the deuterium labeled 1-Decanol.

HY-151547S

MRS4719-d₃
MRS4719-d₃ is the deuterium labeled MRS4719 (HY-151547). MRS4719 is a potent P2X4 receptor antagonist with an IC₅₀ value of 0.503 μM for human P2X4 receptor. MRS4719 can reduce infarct volume and reduce brain atrophy, showing neuroprotective and neuro-rehabilitative activities in ischemic stroke model. MRS4719 also reduces ATP-induced [Ca²⁺]_i influx in primary human monocyte-derived macrophages. MRS4719 can be used to research ischemic stroke.

HY-W014340S

2-Nitro-9H-fluorene-d₉
2-Nitro-9H-fluorene-d₉ is the deuterium labeled 2-Nitro-9H-fluorene.

HY-W001472S

Dimethyl pimelate-d₄
Dimethyl pimelate-d₄ is the deuterium labeled Dimethyl pimelate.

HY-113252S1

2-Methoxyestrone-¹³C₆
2-Methoxyestrone-¹³C₆ is the ¹³C-labeled 2-Methoxyestrone. 2-Methoxyestrone is a methoxylated catechol estrogen and metabolite of estrone, with a pKa of 10.81.

HY-B0154S1

Fluticasone propionate-d₅
Fluticasone propionate-d₅ is deuterium labeled Fluticasone (propionate). Fluticasone propionate, a potent topical anti-inflammatory corticosteroid, is a selective glucocorticoid receptor agonist, with an absolute affinity (KD) of 0.5 nM. Fluticasone propionate shows little or no activity at other steroid receptors. Anti-viral activity.

HY-20390S

Lapatinib impurity 18-d₄
Lapatinib impurity 18-d₄ is deuterium labeled 3-Chloro-4-((3-fluorobenzyl)oxy)aniline.

HY-151893S

7-Methyl-d₃-1-octyl-7,8,8,8-d₃ Alcohol
7-Methyl-d₃-1-octyl-7,8,8,8-d₃ Alcohol is the deuterium labeled 7-Methyl-d3-1-octyl Alcohol.

HY-154741S

6-β-D-Ribofuranosyl-2,4(1H,3H)-pyrimidinedione-₁₅N₂
6-β-D-Ribofuranosyl-2,4(1H,3H)-pyrimidinedione-¹⁵N₂ is ¹⁵N labeled (HY-154741).

HY-13571AS1

Beclometasone dipropionate-d₁₀
Beclometasone dipropionate-d₁₀ is the deuterium labeled Beclometasone dipropionate. Betamethasone dipropionate, the proagent of Betamethasone, is an orally active and potent glucocorticoid with anti-inflammatory and immunosuppressive activity. Betamethasone appears to be an effective inhibitor of LPS-induced inflammation and MMP release.

HY-144149S

3'-p-Hydroxy paclitaxel-d₅
3'-p-Hydroxy paclitaxel-d₅ is the deuterium labeled 3'-p-Hydroxy paclitaxel.

HY-W017758S2

1,3-Propanediol-d₂
1,3-Propanediol-d₂ is the deuterium labeled 1,3-Propanediol. 1,3-Propanediol is produced in nature by the fermentation of glycerol in microorganism.

HY-150659S

Adenosine-5′-triphosphate-d₁₄ disodium
Adenosine-5′-triphosphate-d₁₄ (disodium) is the deuterium labeled Adenosine-5′-triphosphate disodium.

HY-141905S

Isophorone Diamine-¹³C,¹⁵N₂
Isophorone Diamine-¹³C,¹⁵N₂ is the ¹³C and ¹⁵N labeled Isophorone Diamine.

HY-W010918S3

Adenosine 5'-diphosphate-¹³C₅
Adenosine 5'-diphosphate-¹³C₅ (Adenosine diphosphate-¹³C₅) is the ¹³C-labeled Adenosine 5'-diphosphate (HY-W010918). Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P2T-purinoceptors.

HY-W008048S

2',3'-O-Isopropylideneadenosine-¹³C₅
2',3'-O-Isopropylideneadenosine-¹³C₅ is the ¹³C-labeled 2',3'-O-Isopropylideneadenosine (HY-W008048). 2',3'-O-Isopropylideneadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277).

HY-W743098

(S)-(+)-Canadaline-d₃
(S)-(+)-Canadaline-d₃ is the deuterium labeled (S)-(+)-Canadaline.

HY-134160S

5,6-Dihydro-5-Fluorouracil-¹³C,¹⁵N₂
5,6-Dihydro-5-Fluorouracil-¹³C,¹⁵N₂ (5-DHFU-¹³C,¹⁵N₂) is the ¹³C- and ¹⁵N-labeled labeled 5,6-Dihydro-5-Fluorouracil (HY-134160). 5,6-Dihydro-5-Fluorouracil (5-DHFU; 5-Fluorodihydropyrimidine-2,4-dione) is the active metabolite of the thymidylate synthase inhibitor prodrug 5-fluorouracil (HY-90006), which is formed from 5-fluorouracil by dihydropyrimidine dehydrogenase (DPD). 5,6-Dihydro-5-Fluorouracil is cytotoxic to HaCaT keratinocytes (IC₅₀=13.5 μM). Intravenous administration of 5,6-Dihydro-5-Fluorouracil (90 mg/kg/wk) in combination with 5-fluorouracil and the DPD inhibitor eniluracil (HY-10533) slows tumor growth in a rat colon cancer model.

HY-144154S

(Rac)-Rivastigmine-d₆ tartrate
(Rac)-Rivastigmine-d₆ (tartrate) is the deuterium labeled (Rac)-Rivastigmine tartrate.

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