Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (4)

Isotope-Labeled Compounds Related Products (9980):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-141726S

rel-(αR,βR)-β-(2,4-Difluorophenyl)-β-hydroxy-α-methyl-1H-1,2,4-triazole-1-butanoic acid-d₃
rel-(αR,βR)-β-(2,4-Difluorophenyl)-β-hydroxy-α-methyl-1H-1,2,4-triazole-1-butanoic acid-d₃ is the deuterium labeled rel-(αR,βR)-β-(2,4-Difluorophenyl)-β-hydroxy-α-methyl-1H-1,2,4-triazole-1-butanoic acid.

HY-17495AS

Carteolol-d₉ hydrochloride
Carteolol-d₉ (hydrochloride) is the deuterium labeled Carteolol hydrochloride. Carteolol hydrochloride (OPC-1085 hydrochloride) is a non-selective beta blocker used to treat glaucoma.

HY-B0286S

Chlorpheniramine-d₆ maleate
Chlorpheniramine-d₆ (maleate) is the deuterium labeled Chlorpheniramine maleate.

HY-W052508S

Norquetiapine-d₈
Norquetiapine-d8 (N-Desalkylquetiapine-d8) is the deuterium labeled Norquetiapine.Norquetiapine ( N-Desalkylauetiapine), a metabolite of Quetiapine (HY-14544), is a selective HCN1 channel inhibitor, with an IC₅₀ of 13.9 μM. Norquetiapine selectively inhibits noradrenaline reuptake, is a partial 5-HT_1A (K_i = 45 nM) receptor agonist, and acts as an antagonist at presynapticα2 (K_i = 237 nM), 5-HT_2C(K_i = 107 nM), and 5-HT₇ (K_i = 76 nM) receptors. Norquetiapine blocks the human cardiac sodium channel Nav1.5 in a state-dependent manner. Norquetiapine shows partial anti-inflammatory effects in LPS (HY-D1056) injected C57BL/6 mice. Norquetiapine can be used for the study of depression and inflammation.

HY-136907S

(S)-(-)-Verapamil-d₃ hydrochloride
(S)-(-)-Verapamil-d₃ (hydrochloride) is the deuterium labeled (S)-(-)-Verapamil hydrochloride.

HY-B2120S

2-Amino-5-nitrobenzophenone-d5
2-Amino-5-nitrobenzophenone-d₅ is the deuterium labeled 2-Amino-5-nitrobenzophenone.

HY-139509S

Capsiamide-d₃
Capsiamide-d₃ is the deuterium labeled Capsiamide.

HY-17430S

Amprenavir-d₄
Amprenavir-d₄ is the deuterium labeled Amprenavir. Amprenavir (VX-478) is a HIV protease inhibitor (Ki=0.6 nM) used to treat HIV infection. Amprenavir is also a SARS-CoV 3CLpro inhibitor with an IC₅₀ of 1.09 μM.

HY-15388S

Tazarotene-d₈
Tazarotene-d₈ is the deuterium labeled Tazarotene. Tazarotene (AGN 190168) is a selective retinoic acid receptor (RAR) agonist for the treatment of plaque psoriasis and acne vulgaris.

HY-13738S2

Raloxifene-d₄ hydrochloride		98.61%
Raloxifene-d₄ (hydrochloride) is the deuterium labeled Raloxifene. Raloxifene (Keoxifene) is a benzothiophene-derived selective estrogen receptor modulator (SERM). Raloxifene has estrogen-agonistic effects on bone and lipids and estrogen-antagonistic effects on the breast and uterus. Raloxifene is used for breast cancer and osteoporosis research.

HY-139508S

4-Benzhydryloxy-piperidine-d₅
4-(Diphenylmethoxy)piperidine-d₅ is the deuterium labeled 4-(Diphenylmethoxy)piperidine.

HY-N0125S

Diosmetin-d₃
Diosmetin-d₃ is the deuterium labeled Diosmetin. Diosmetin is a natural flavonoid which inhibits human CYP1A enzyme activity with an IC50 of 40 μM in HepG2 cell.

HY-141753S

N-Desmethylcarboxy terbinafine-d₇
N-Desmethylcarboxy Terbinafine-d₇ is the deuterium labeled N-Desmethylcarboxy Terbinafine.

HY-132770S

Propafenone Dimer Impurity-d10
Propafenone Dimer Impurity-d₁₀ is the deuterium labeled Propafenone Dimer Impurity.

HY-139524S

Desmethyl atomoxetine-d7 hydrochloride
Desmethyl atomoxetine-d₇ hydrochloride is the deuterium labeled Desmethyl atomoxetine hydrochloride.

HY-66006AS

4-Acetaminophen sulfate-d₃ potassium
4-Acetaminophen sulfate-d₃ (potassium) is the deuterium labeled 4-Acetaminophen sulfate potassium.

HY-B1662S1

(Rac)-Hexestrol-d₆
(Rac)-Hexestrol-d₆ is the deuterium labeled (Rac)-Hexestrol.

HY-132795S

Des(1-cyclohexanol) Venlafaxine-d₆
Des(1-cyclohexanol) Venlafaxine-d₆ is the deuterium labeled Des(1-cyclohexanol) Venlafaxine.

HY-76326S

(S)-3-((1-methylpyrrolidin-2-yl)methyl)-5-(2-(phenylsulfonyl)ethyl)-1H-indole-d₃
(S)-3-((1-methylpyrrolidin-2-yl)methyl)-5-(2-(phenylsulfonyl)ethyl)-1H-indole-d₃ is the deuterium labeled (S)-3-((1-methylpyrrolidin-2-yl)methyl)-5-(2-(phenylsulfonyl)ethyl)-1H-indole.

HY-Z3334S

N-Acetyl Sitagliptin-d₃
N-Acetyl Sitagliptin-d₃ is the deuterium labeled N-Acetyl Sitagliptin.

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