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  4. Fluorescent Dye

Fluorescent Dye

Fluorescence is a phenomenon of photoluminescence in luminescence. When an atom is irradiated by light, some electrons around the nucleus jump from their original orbitals to higher energy orbitals under the influence of light energy, i.e., from the ground state to the first or second excited single-line state, etc. Due to the instability of the first or second excited singlet state, the electron returns from the excited singlet state to the ground state accompanied by released energy, resulting in fluorescence.

Fluorescent dyes can be covalently bound or physically adsorbed in the structure of the substance. The fluorescence properties allow for the characterization, localization and quantitative analysis of the labeled object. Fluorescent dyes have shown great potential for the detection of proteins, nucleic acids, cells, and immunoassays, attributed to the advantages in non-radioactive contamination, simple experimental operation and easy observation.

Fluorescent dyes have penetrated many fields such as pharmacology, physiology, environmental science, and information science, as well as functional studies of proteins and drug screening.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-D0097
    7-Fluorobenzofurazan-4-sulfonic acid ammonium
    		98.96%
    7-Fluorobenzofurazan-4-sulfonic acid ammonium is a fluorescent label. 7-Fluorobenzofurazan-4-sulfonic acid ammonium can be used for detecting dissolved thiol-disulfide (e.g., Cys, GSH).
    7-Fluorobenzofurazan-4-sulfonic acid ammonium
  • HY-D2395
    B-Phycoerythrin
    B-Phycoerythrin (B-PE) is a light-harvesting pigment protein that can be isolated from the red alga Porphyridium cruentum. The absorption spectrum of B-Phycoerythrin peaks at 545 nm and 563 nm, with a shoulder at 498 nm.
    B-Phycoerythrin
  • HY-P4725
    Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2
    		99.69%
    Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 is a fluorogenic substrate, that can be used for the fluorescence screening assay.
    Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2
  • HY-160840
    SPB-AAD
    SPB-AAD is a BFPX probe. SPB-AAD has covalent capture of in vitro assembled MEF2/DNA and NFAT1/DNA complexes.
    SPB-AAD
  • HY-136957
    Fluorescein-6-isothiocyanate
    		98.03%
    Fluorescein-6-isothiocyanate is a fluorescent isomeric haptenic probes with Kds of 8.74, 2.72 and 1.88 for N-Acetyl-L-Lysine, normal mouse IgG and 4-4-20, respectively.
    Fluorescein-6-isothiocyanate
  • HY-D0813
    Zincon sodium
    Zincon sodium is an excellent colorimetric reagent for the detection of zinc and copper ions in aqueous solution. Zincon sodium can be used for the determination of zinc, copper, and cobalt ions in metalloproteins.
    Zincon sodium
  • HY-D1325
    Cyanine5.5 alkyne chloride
    		99.00%
    Cyanine5.5 alkyne chloride is an alkynyl-modified near-infrared (NIR) fluorescent dye (Ex=678 nm, Em=694 nm). Cyanine5.5 alkyne chloride can react with azides for click chemistry labeling.
    Cyanine5.5 alkyne chloride
  • HY-124197
    Coumarin hydrazine
    Coumarin hydrazine is a fluorescent chemical probe (λex=420–450/λem=468nm) to label cellular protein- and lipid-bound carbonyls.
    Coumarin hydrazine
  • HY-D1026
    CUG
    		99.20%
    CUG (3-Carboxyumbelliferyl-β-D-galactopyranoside) is a fluorogenic substrate (λex=386, λem=445 nm, ε=32K).
    CUG
  • HY-D0350
    Direct Yellow 50
    Direct Yellow 50 is a good dyeing agent for cotton fabrics.
    Direct Yellow 50
  • HY-D2639
    TPE-PY
    TPE-PY is a fluorescent dye targeting mitochondria, which has cationic and lipophilic characteristics, enabling specific targeting of mitochondria. TPE-PY functions through the aggregation-induced emission (AIE) mechanism. TPE-PY mechanism of action is based on the restriction of intramolecular rotation (RIR), which enhances fluorescence in the aggregated state. TPE-PY is mainly used in the field of biological imaging, especially for the specific staining of mitochondria in living cells, facilitating the observation of the location, morphology, and quantity of mitochondria.
    TPE-PY
  • HY-D2864
    Aza-CyBz
    Aza-CyBz is a selective NaCl-responsive fluorescent probe. Aza-CyBz visualizes plant salt stress by forming ordered aggregates with NaCl, leading to near-infrared fluorescence quenching. Aza-CyBz acts via electrostatic interaction between the cationic cyanine dye and NaCl to form J-aggregates, causing fluorescence quenching with a detection limit of 170 μM.
    Aza-CyBz
  • HY-D1196
    Direct Blue 71
    Direct Blue 71 is a good dyeing agent for cotton fabrics and can be adsorbed by palm ash and removed from the aqueous solution.
    Direct Blue 71
  • HY-D2268
    QM-FN-SO3
    QM-FN-SO3 is a BBB-penetrable near-infrared (NIR) aggregation-induced emission (AIE)-active probe for Aβ plaques. QM-FN-SO3 can be used for in vivo detection of Aβ plaques. QM-FN-SO3 has ultra-high S/N ratio, binding affinity, and high-performance NIR emission.
    QM-FN-SO3
  • HY-D2367
    Rhodamine B NHS ester
    Rhodamine B NHS ester is a fluorophore featuring an NHS ester. Rhodamine B is a fluorescent dye which is used in fluorescence-based assays in vivo. NHS esters are highly reactive towards amines, forming amides under mild conditions.
    Rhodamine B NHS ester
  • HY-W267364
    Coumarin 343
    Coumarin 343 (C343) is a hydrophilic fluorescent probe for the micro water pool. λem is approximately 425 nm andλem is approximately from 425 nm to 550 nm by RF-1500.
    Coumarin 343
  • HY-155327B
    Cy3-PEG2-endo-BCN bromide
    Cy3-PEG2-endo-BCN bromide is the bromide salt form of Cy3-PEG2-endo-BCN (HY-155327). Cy3-PEG2-endo-BCN bromide is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 2 PEG units. Cy3-PEG2-endo-BCN bromide contains the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
    Cy3-PEG2-endo-BCN bromide
  • HY-D1906
    BDP R6G NHS ester
    		99.40%
    BDP R6G NHS ester is a borodipyrromethane fluorophore, which contains a NHS ester group that can react with amine groups (-NH2) in proteins or other molecules to form stable amide bonds (Ex/Em = 530/548 nm).
    BDP R6G NHS ester
  • HY-W026772S1
    Fluorene-d8
    Fluorene-d8 is the deuterium labeled Fluorene (HY-W026772). Fluorene is an orally active polycyclic aromatic hydrocarbon (PAH) and a precursor to other fluorene-based compounds. Fluorene and its derivatives serve as dye precursors for fluorene synthesis. In A549 cells, Fluorene induces oxidative stress and inflammatory responses by increasing ROS and SOD generation, exacerbating lipid peroxidation, modulating antioxidant enzyme activity, and upregulating the expression of pro-inflammatory factors TNF-α and IL-6. In vivo, Fluorene exhibits anxiolytic activity. Fluorene holds potential for research in inflammation and neurological disorders.
    Fluorene-d<sub>8</sub>
  • HY-147169
    Biotin-X-NTA
    		98.11%
    Biotin-X-NTA can be used for detecting histidine-tagged proteins immobilized on nitrocellulose membranes.
    Biotin-X-NTA
Cat. No. Product Name / Synonyms Application Reactivity