2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-113215
    Allotetrahydrocortisol
    		99.53%
    Allotetrahydrocortisol (5a-Tetrahydrocortisol) is a metabolite of Cortisol. Cortisol is the main glucocorticoid in human. It is produced in adrenal cortex and plays a crucial role in many physiological processes.
    Allotetrahydrocortisol
  • HY-B0451AR
    Dopamine hydrochloride (Standard)
    Dopamine (hydrochloride) (Standard) is the analytical standard of Dopamine (hydrochloride). This product is intended for research and analytical applications. Dopamine hydrochloride (ASL279) is a catecholamine neurotransmitter that is produced in the substantia nigra, ventral tegmental area, and hypothalamus of the brain. Dopamine hydrochloride (ASL279) plays several important roles in the brain and body. Dopamine hydrochloride (ASL279) acts through D2 dopamine receptors to induce endocytosis of VEGFR2, which is critical for promoting angiogenesis.
    Dopamine hydrochloride (Standard)
  • HY-164804
    N-Lactylvaline
    		99.93%
    N-Lactylvaline is an endogenous metabolite that can be identified in patients with the intermediate type of maple syrup urine disease.
    N-Lactylvaline
  • HY-W019838S
    D-Erythro-dihydrosphingosine-d7
    		99.00%
    D-Erythro-dihydrosphingosine-d7 is the deuterium labeled D-Erythro-dihydrosphingosine. D-Erythro-dihydrosphingosin directly inhibits cytosolic phospholipase A2α (cPLA2α) activity.
    D-Erythro-dihydrosphingosine-d<sub>7</sub>
  • HY-B0412R
    Estriol (Standard)
    Estriol (Standard) is the analytical standard of Estriol. This product is intended for research and analytical applications.
    Estriol (Standard)
  • HY-W016415
    7-Methyluric acid
    		99.0%
    7-Methyluric acid is a metabolite of caffeine. 7-Methyluric acid can be detected in urine.
    7-Methyluric acid
  • HY-N0092R
    Inosine (Standard)
    Inosine (Standard) is the analytical standard of Inosine. This product is intended for research and analytical applications. Inosine is an endogenous purine nucleoside produced by catabolism of adenosine. Inosine has anti-inflammatory, antinociceptive, immunomodulatory and neuroprotective effects. Inosine is an agonist for adenosine A1 (A1R) and A2A (A2AR) receptors. In Vitro:Inosine dose-dependently stimulates cAMP production mediated through the A2AR.
    Inosine dose-dependently induces hA2AR-mediated ERK1/2 phosphorylation.
    Inosine (100 μM; 24 hours) reduces oxidative stress in MES 23.5 cells cultured with astrocytes.
    In Vivo:Inosine (10-100 mg/kg; i.p.) exhibits antinociceptive effect in mice.
    Inosine (Standard)
  • HY-111646
    N6-Etheno 2'-deoxyadenosine
    		99.48%
    N6-Etheno 2'-deoxyadenosine is a reactive oxygen species (ROS)/reactive nitrogen species (RNS)-induced DNA oxidation product, used as a biomarker to evaluate chronic inflammation and lipid peroxidation in animal or human tissues.
    N6-Etheno 2'-deoxyadenosine
  • HY-W015675
    4-Hydroxycyclohexanecarboxylic acid
    4-Hydroxycyclohexanecarboxylic acid belongs to the class of organic compounds known as cyclohexanols.
    4-Hydroxycyclohexanecarboxylic acid
  • HY-W014125
    Undecanedioic acid
    		≥98.0%
    Undecanedioic acid is associated with intercellular matrix macromolecules and specifically with elastin.
    Undecanedioic acid
  • HY-B0935S1
    Benzyl benzoate-d12
    		99.85%
    Benzyl benzoate-d12 is the deuterium labeled Benzyl benzoate. Benzyl benzoate (Benzoic acid benzyl ester) is a fragrance ingredient in cosmetic products. Benzyl benzoate can be used for the research of Scabies and Demodex-associated inflammatory skin conditions.
    Benzyl benzoate-d<sub>12</sub>
  • HY-P3186
    Glucose dehydrogenase, recombinant Microorganisms
    Glucose dehydrogenase, recombinant Microorganisms is a FDA-dependent oxidoreductase. Glucose dehydrogenase (GDH) catalyzes the oxidation of β-D-glucose to β-D-glucono-1,5-lactone with simultaneous reduction of the cofactor NADP+ to NADPH or, to a lesser extent, NAD+ to NADH. Glucose dehydrogenase (GDH) accepts both NAD+ and NADP+ as cofactors and can be used for the regeneration of NADH and NADPH.
    Glucose dehydrogenase, recombinant Microorganisms
  • HY-17363S1
    Dimethyl fumarate-d2
    		99.20%
    Dimethyl fumarate-d2 is the deuterium labeled Dimethyl fumarate. Dimethyl fumarate (DMF) is an orally active and brain-penetrant Nrf2 activator and induces upregulation of antioxidant gene expression. Dimethyl fumarate induces necroptosis in colon cancer cells through GSH depletion/ROS increase/MAPKs activation pathway, and also induces cell autophagy. Dimethyl fumarate can be used for multiple sclerosis research.
    Dimethyl fumarate-d<sub>2</sub>
  • HY-145505
    1-Oleoyl-2-hydroxy-sn-glycero-3-PG sodium
    		99.0%
    1-Oleoyl-2-hydroxy-sn-glycero-3-PG (18:1 Lyso PE) sodium is a lysophospholipid containing oleic acid (18:1) at the sn-1 position. It can be used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.
    1-Oleoyl-2-hydroxy-sn-glycero-3-PG sodium
  • HY-B0633D
    Hyaluronic acid sodium (MW 200-1560)
    		99.41%
    Hyaluronic acid sodium (MW 200-1560) is a biopolymer composed of repeating disaccharide units with a molecular weight of 1000-2000. Hyaluronic acid sodium (MW 200-1560) has a wide range of applications.
    Hyaluronic acid sodium (MW 200-1560)
  • HY-79635
    Methyl indole-3-carboxylate
    		99.89%
    Methyl indole-3-carboxylate is a Sorangium metabolite. Methyl indole-3-carboxylate shows weak activity against Gram-positive Nocardia sp with a MIC of 33.3 μg/mL.
    Methyl indole-3-carboxylate
  • HY-N1981R
    Triolein (Standard)
    Triolein (Standard) is the analytical standard of Triolein. This product is intended for research and analytical applications. Triolein is a symmetric triacylglycerol that reduces upregulation of MMP-1 and has strong antioxidant and anti-inflammatory activities.
    Triolein (Standard)
  • HY-141466A
    Crotonyl-CoA tetrasodium
    Crotonyl-CoA tetrasodium is the tetrasodium salt form of Crotonyl-CoA (HY-141466). Crotonyl-CoA tetrasodium is an intermediate in the fermentation of butyric acid, and in the metabolism of lysine and tryptophan. Crotonyl-CoA tetrasodium is important in the metabolism of fatty acids and amino acids.
    Crotonyl-CoA tetrasodium
  • HY-N7092S9
    D-Fructose-d4
    		99.9%
    D-Fructose-d4 is the deuterium labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants.
    D-Fructose-d<sub>4</sub>
  • HY-113217S
    Cholesteryl oleate-d7
    		≥99.0%
    Cholesteryl oleate-d7 is deuterium labeled Cholesteryl oleate. Cholesteryl oleate is an ester compound formed from Cholesterol (HY-N0322) and Oleic acid (HY-N1446), which is involved in lipid transport, storage and cell membrane formation in living organisms. Cholesteryl oleate may serve as a potential biomarker for prostate cancer. Cholesteryl oleate can also prepare cationic solid lipid nanoparticles (SLNs) for efficient gene silencing.
    Cholesteryl oleate-d<sub>7</sub>
Cat. No. Product Name / Synonyms Application Reactivity