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  3. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9978):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-12767S
    4-Hydroxyphenyl Carvedilol-d5
    4-Hydroxyphenyl Carvedilol-d5 is the deuterium labeled 4-Hydroxyphenyl Carvedilol.
    4-Hydroxyphenyl Carvedilol-d<sub>5</sub>
  • HY-W004113S
    3,5-Dichlorophenol-d3
    3,5-Dichlorophenol-d3 is the deuterium labeled 3,5-Dichlorophenol.
    3,5-Dichlorophenol-d<sub>3</sub>
  • HY-W220946S
    2-Chlorobutanoic acid-d6
    2-Chlorobutanoic acid-d6 is the deuterium labeled 2-Chlorobutanoic acid.
    2-Chlorobutanoic acid-d<sub>6</sub>
  • HY-N0113BS
    Hordenine-d6 hydrochloride
    Hordenine-d6 (Ordenina-d6; Peyocactine-d6) hydrochloride is deuterium-labeled Hordenine (hydrochloride) (HY-N0113B).
    Hordenine-d<sub>6</sub> hydrochloride
  • HY-W012478S
    6-Phenyl-2-thiouracil-13C,15N2
    6-Phenyl-2-thiouracil-13C,15N2 is the 13C, 15N labeled 6-Phenyl-2-thiouracil.
    6-Phenyl-2-thiouracil-<sup>13</sup>C,<sup>15</sup>N<sub>2</sub>
  • HY-100642S
    3-O-Methyltolcapone-d7
    99.0%
    3-O-Methyltolcapone-d7 (Ro 40-7591 d7) is a deuterium labeled 3-O-Methyltolcapone (HY-174062). 3-O-Methyltolcapone (Ro 40-7591) is a metabolite of Tolcapone (HY-17406). Tolcapone (Ro 40-7592) is a selective, potent and orally active COMT inhibitor with an IC50of 773 nM. Tolcapone can inhibits α-syn and Aβ42 oligomerization and fibrillogenesis. Tolcapone can cause oxidative stress and induce cancer cells apoptosis and ROS production. Tolcapone can be used for the researches of cancer and neurological disease, such as Parkinson disease and neuroblastoma.
    3-O-Methyltolcapone-d<sub>7</sub>
  • HY-W012684S1
    Ethane-1,2-diamine-d4 dihydrochloride
    Ethane-1,2-diamine-d4 (Ethylenediamine-d4) dihydrochloride is a deuterium labeled Ethane-1,2-diamine.
    Ethane-1,2-diamine-d<sub>4</sub> dihydrochloride
  • HY-W010482S
    3-Ethylaniline-d5
    3-Ethylaniline-d5 is the deuterium labeled 3-Ethylaniline (HY-W010482). 3-Ethylaniline is metabolized in vivo to electrophilic intermediates that covalently bind to DNA and that adducts are formed in the DNA of bladder. 3-Ethylaniline can be used for the research of bladder cancer.
    3-Ethylaniline-d<sub>5</sub>
  • HY-113313S2
    Aldosterone-d4
    99.30%
    Aldosterone-d4 is the deuterium labeled Aldosterone. Aldosterone is the primary mineralocorticoid. Aldosterone is a steroid hormone, and it is synthesized and secreted in response to renin-angiotensin system activation (RAS) or high dietary potassium by t
    Aldosterone-d<sub>4</sub>
  • HY-126182S4
    Desacetyl Diltiazem-d4 hydrochloride
    Desacetyl Diltiazem-d4 (hydrochloride) is the deuterium labeled Desacetyl Diltiazem hydrochloride.
    Desacetyl Diltiazem-d<sub>4</sub> hydrochloride
  • HY-17598S
    Rafoxanide-13C6
    Rafoxanide 13C6 is a labeled Rafoxanide (HY-17598). Rafoxanide is a salicylanilide used as an antiparasitic agent.
    Rafoxanide-<sup>13</sup>C<sub>6</sub>
  • HY-W002094S
    Cyclopropane-1,1-dicarboxylic acid-d4
    Cyclopropane-1,1-dicarboxylic acid-d4 is the deuterium labeled Cyclopropane-1,1-dicarboxylic acid.
    Cyclopropane-1,1-dicarboxylic acid-d<sub>4</sub>
  • HY-78467S
    4-Bromo-2-fluoro-N-methylbenzamide-d3
    4-Bromo-2-fluoro-N-methylbenzamide-d3 is the deuterium labeled 4-Bromo-2-fluoro-N-methylbenzamide (HY-78467).
    4-Bromo-2-fluoro-N-methylbenzamide-d<sub>3</sub>
  • HY-W017443S3
    L-Asparagine-15N2,d3 monohydrate
    L-Asparagine-15N2,d3 monohydrate is the deuterium and 15N-labeled L-Asparagine monohydrate (HY-W017443). L-Asparagine monohydrate is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine monohydrate can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia.
    L-Asparagine-<sup>15</sup>N<sub>2</sub>,d<sub>3</sub> monohydrate
  • HY-W704197
    N-tert-Butylcarbamoyl-L-tert-leucine-d9
    N-tert-Butylcarbamoyl-L-tert-leucine-d9 is the deuterium labeled N-tert-Butylcarbamoyl-L-tert-leucine (HY-I0208).
    N-tert-Butylcarbamoyl-L-tert-leucine-d<sub>9</sub>
  • HY-101392S1
    Harmane-d2
    Harmane-d2 is the deuterium labeled Harmane. Harmane, a β-Carboline alkaloid (BCA), is a potent neurotoxin that causes severe action tremors and psychiatric manifestations. Harmane shows 1000-fold selectivity for I1-Imidazoline receptor (IC50=30 nM) over α2-adrenoceptor (IC50=18 μM). Harmane is also a potent and selective inhibitor of monoamine oxidase (MAO) (IC50s=0.5 and 5 μM for human MAO A/B, respectively).
    Harmane-d<sub>2</sub>
  • HY-113266S
    Valerylcarnitine-d9
    Valerylcarnitine-d9 (C5:0 L-carnitine-d9) is the deuterium labeled Valerylcarnitine (HY-113266). Valerylcarnitine is an endogenous metabolite, belonging to the short-chain acylcarnitines.
    Valerylcarnitine-d<sub>9</sub>
  • HY-W008507S1
    (R)-2,3-Dihydroxypropanal-d2
    (R)-2,3-Dihydroxypropanal-d2 is the deuterium labeled 3-O-Methyl-D-glucopyranose.
    (R)-2,3-Dihydroxypropanal-d<sub>2</sub>
  • HY-A0069AS
    Doxylamine-d5
    Doxylamine-d5 is deuterium labeled Doxylamine.
    Doxylamine-d<sub>5</sub>
  • HY-129912S
    N1,N8-Diacetylspermidine-d6
    N1,N8-Diacetylspermidine-d6 is the deuterium labeled N1,N8-Diacetylspermidine (HY-129912). N1,N8-Diacetylspermidine is a polyamines in the human urine. N1,N8-Diacetylspermidine is useful as prognostic indicators after treatment and during follow-up examination of cancer patients.
    N1,N8-Diacetylspermidine-d<sub>6</sub>