2. Signaling Pathways
  3. Anti-infection
  4. Fungal

Fungal

Fungal

Related Products

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An antifungal agent is a drug that selectively eliminates fungal pathogens from a host with minimal toxicity to the host.

Classes: 1. Polyene Antifungal Drugs: Amphotericin, nystatin, and pimaricin interact with sterols in the cell membrane (ergosterol in fungi, cholesterol in humans) to form channels through which small molecules leak from the inside of the fungal cell to the outside. 2. Azole Antifungal Drugs: Fluconazole, itraconazole, and ketoconazole inhibit cytochrome P450-dependent enzymes (particularly C14-demethylase) involved in the biosynthesis of ergosterol, which is required for fungal cell membrane structure and function. 3. Allylamine and Morpholine Antifungal Drugs: lylamines (naftifine, terbinafine) inhibit ergosterol biosynthesis at the level of squalene epoxidase. The morpholine drug, amorolfine, inhibits the same pathway at a later step. 4. Antimetabolite Antifungal Drugs: 5-Fluorocytosine acts as an inhibitor of both DNA and RNA synthesis via the intracytoplasmic conversion of 5-fluorocytosine to 5-fluorouracil.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N15029
    Destomycin A
    		Inhibitor
    Destomycin A is an aminoglycoside antibiotic with antibacterial (Gram-positive bacteria, Gram-negative bacteria), antifungal and anthelmintic activities. Destomycin A inhibits the polypeptide synthesis in cells of Escherichia coli and stimulation of adenylate cyclase in animal tissues.
    Destomycin A
  • HY-N5187
    Edeine A1
    		Inhibitor
    Edeine A1 can inhibit DNA replication and protein biosynthesis, and has anti-Gram-positive bacteria, Gram-negative bacteria, fungi and yeast activities.
    Edeine A1
  • HY-N4136R
    Lonicerin (Standard)
    		Inhibitor
    Lonicerin (Standard) (Veronicastroside (Standard)) is the analytical standard of Lonicerin (HY-N4136). This product is intended for research and analytical applications. Lonicerin is a flavonoid with multiple biological activities. Lonicerin inhibits xanthine oxidase with an IC50 of 37.4 µg/mL. Lonicerin inhibits alginate secretion protein (AlgE). Lonicerin inhibits P. aeruginosa and C. albicans. Lonicerin has anti-inflammatory, anti-arthritic, antioxidant, antifungal, anti-bacterial, and neuroprotective properties.
    Lonicerin (Standard)
  • HY-P10916
    Micafungin metabolite M1
    		Inhibitor
    Micafungin metabolite M1 is an active metabolite of Micafungin (HY-17579), which is metabolized by arylsulfatase and exhibits antifungal activity. Micafungin metabolite M1 can be used for research on deep fungal infections caused by Candida and Aspergillus species.
    Micafungin metabolite M1
  • HY-126200R
    Fenpropidin (Standard)
    		Inhibitor
    Fenpropidin (Standard) is the analytical standard of Fenpropidin (HY-126200). This product is intended for research and analytical applications. Fenpropidin, a piperidine, is a fungicide used to control a range of diseases in cereals. Fenpropidin shows antifungal activity against different human pathogenic yeasts and filamentous fungi.
    Fenpropidin (Standard)
  • HY-B1345R
    Piroctone olamine (Standard)
    		Inhibitor
    Piroctone olamine (Standard) is the analytical standard of Piroctone olamine. This product is intended for research and analytical applications. Piroctone olamine is a pyridine derivate. It is known to have a fungicidal effect.
    Piroctone olamine (Standard)
  • HY-163635
    Antifungal agent 102
    		Inhibitor
    Antifungal agent 102 (compound C20) is a antifungal agent aganist B. cinerea with the EC50 of 1.23 μg/mL.
    Antifungal agent 102
  • HY-B2026R
    Propamocarb (Standard)
    		Inhibitor
    Propamocarb (Standard) is the analytical standard of Propamocarb. This product is intended for research and analytical applications. Propamocarb is a systemic fungicide. Propamocarb is widely used to protect cucumbers, tomatoes and other plants from pathogens.
    Propamocarb (Standard)
  • HY-N14008
    Carriomycin
    		Inhibitor
    Carriomycin is an antibiotic that can be isolated from Streptomyces hygroscopicus. Carriomycin can inhibit Gram-positive bacteria, mycobacteria, yeasts and fungi, and is also an effective anticoccidial agent.
    Carriomycin
  • HY-P5549
    Hb 98–114
    		Inhibitor
    Hb 98-114, the amino acids 98-114 of the alpha subunit of bovine hemoglobin, is an antimicrobial peptide. Hb 98-114 is active against several yeast and filamentous fungi (MIC: 2.1 μM-12.5 μM).
    Hb 98–114
  • HY-136926
    Candicidin A3
    		Inhibitor
    Candicidin A3 (FR-008I) is an antifungal antibiotic with significant biological activity. Candicidin A3 can effectively inhibit the growth of fungi through its unique three-dimensional structure and seven-membered ring geometry. The absolute configuration of Candicidin A3 is a specific arrangement of multiple chiral centers, which may affect its biological activity and interaction with targets. Candicidin A3 can be used as a potential drug to inhibit fungal infections.
    Candicidin A3
  • HY-116034
    Arasertaconazole
    		Inhibitor
    Arasertaconazole is a potent 14α-lanosterol demethylase inhibitor. Arasertaconazole has antifungal and antibacterial activity.
    Arasertaconazole
  • HY-N14979
    Dermostatin A
    		Inhibitor
    Dermostatin A is a polyene antibiotic with antifungal activity that can be used in the study of fungal infections.
    Dermostatin A
  • HY-117872
    Sartorypyrone A
    Sartorypyrone A (20-O-Acetylsartorypyrone D) is a monocyclic terpenoid isolated from the soil fungus Neosartorya fischeri. Sartorypyrone A exhibits in vitro growth inhibitory activity against MCF-7, NCI-H460, and A375-C5 cell lines, and has potential anticancer properties.
    Sartorypyrone A
  • HY-P5591
    PAF26
    		Inhibitor 98.89%
    PAF26 is an antimicrobial peptide against phytopathogenic fungi Penicillium digitatum, Penicillium italicum and Botrytis cinerea.
    PAF26
  • HY-D0008R
    Brilliant green (Standard)
    		Inhibitor
    Brilliant green (Standard) is the analytical standard of Brilliant green. This product is intended for research and analytical applications. Brilliant green is a cationic dye used to color silk and wool. Brilliant green inhibits propagation of mold, intestinal parasites and fungus. Brilliant green is effective against Gram-positive bacteria.
    Brilliant green (Standard)
  • HY-W013973R
    p-Terphenyl (Standard)
    p-Terphenyl (Standard) is the analytical standard of p-Terphenyl. This product is intended for research and analytical applications. p-Terphenyl is a p-terphenyl that can be isolated from Aspergillus of the genus Thelephora. p-Terphenyl showed significant anti-tumor and anti-metastatic effects in xenograft models of gastric and pancreatic cancer. Derivatives of p-Terphenyl also have anti-inflammatory or anti-proliferative effects.
    p-Terphenyl (Standard)
  • HY-121109R
    Benalaxyl (Standard)
    		Inhibitor
    Benalaxyl (Standard) is the analytical standard of Benalaxyl (HY-121109). This product is intended for research and analytical applications. Benalaxyl is a fungicide. Benalaxyl has good control of blue mould (Peronospora tubacina).
    Benalaxyl (Standard)
  • HY-N14486
    Neihumicin
    		Inhibitor
    Neihumicin is resistant to beer Saccharomyces yeast ATCC 9763 and Penicillium italium Wehmer, but not to bacteria.
    Neihumicin
  • HY-Y0510
    Nitrofungin
    		Inhibitor 99.82%
    Nitrofungin (2-Chloro-4-nitrophenol) is an antifungal agent, and can also be degraded by some bacteria.
    Nitrofungin
Cat. No. Product Name / Synonyms Application Reactivity