1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-179038
    PYO12
    Inhibitor
    PYO12 is a 3-phenyl-4-phenoxypyrazole type antibacterial compound. PYO12 exhibits selective activity against Gram-positive bacteria with MIC for S. aureus, B. subtilis, S. pneumoniae, and MRSA of 1, 1, 1, and 4 μg/mL respectively. PYO12 has no activity against Gram-negative bacteria. PYO12 can significantly increase bacterial membrane permeability and significantly upregulate cell wall stress-related genes, possibly by binding to the C55-PP part of lipid II. PYO12 shows a concentration-dependent bactericidal effect, has low toxicity to mammalian cells, and does not cause hemolysis. PYO12 can be used to develop new antibiotics targeting bacterial cell wall synthesis.
    PYO12
  • HY-173375
    Mycobacterium Tuberculosis-IN-8
    Inhibitor
    Mycobacterium Tuberculosis-IN-8 (Compound 6g) is a selective inhibitor of Mycobacterium tuberculosis (MTB) with an MIC value of 6.25 µg/mL against MTB H37Rv. Mycobacterium Tuberculosis-IN-8 shows potent antitubercular activities, inhibiting mycolic acid biosynthesis critical for bacterial cell wall integrity. Mycobacterium Tuberculosis-IN-8 is promising for research of antitubercular agents.
    Mycobacterium Tuberculosis-IN-8
  • HY-106322
    IO-21
    IO-21 (Compound 3) is a candidate cytoprotective agent. IO-21 exhibits a marked cytoprotective effect. IO-21 shows a potent inhibitory activity against HCl•ethanol-induced lesions. IO-21 shows a MIC of 50 μg/mL against Helicobacter pylori 7795. IO-21 can be used in the research of gastric mucosal ulcers.
    IO-21
  • HY-B0529AR
    Azlocillin sodium salt (Standard)
    Inhibitor
    Azlocillin (sodium salt) (Standard) is the analytical standard of Azlocillin (sodium salt). This product is intended for research and analytical applications. Azlocillin sodium salt (Sodium azlocillin), a semisynthetic penicillin, is a broad spectrum β-lactam antibiotic. Azlocillin sodium salt shows antipseudomonal activity, and also potent against the malarial parasite Plasmodium falciparum.
    Azlocillin sodium salt (Standard)
  • HY-W710314
    3,4-Dimethoxy-1,2-dimethyl-9H-carbazole
    3,4-Dimethoxy-1,2-dimethyl-9H-carbazole is a carbazole alkaloid that can be used in the synthesis of baccamycin.
    3,4-Dimethoxy-1,2-dimethyl-9H-carbazole
  • HY-N13940
    Argyrin D
    Inhibitor
    Argyrin D is a natural cyclic, non-ribosomal peptide that displays a promising antimicrobial activity against Pseudomonas aeruginosa.
    Argyrin D
  • HY-125322
    Reveromycin C
    Reveromycin C is a polyketide originally isolated from Streptomyces that has antifungal activity against C. albicans (MICs=2.0 and >500 μg/mL at pH 3 and 7.4, respectively). Reveromycin C inhibits EGF-induced mitogenic activity in the Balb/MK mouse epidermal cell line. It also reverses the morphology of sarcoma-virus-transformed NRK rat kidney cells (EC50=1.58 μg/mL) and inhibits proliferation of KB cells and K562 human chronic myelogenous leukemia cells (IC50=2.0 μg/mL for both).
    Reveromycin C
  • HY-N14532
    Pyrrolomycin E
    Inhibitor
    Pyrrolomycin E is a pyrrole antibiotic. Pyrrolomycin E has anti-Gram-positive bacteria, anti-Gram-negative bacteria and anti-individual fungi activity.
    Pyrrolomycin E
  • HY-N14609
    Respinomycin A2
    Inhibitor
    Respinomycin A2 is an anthracycline antibiotic that causes the differentiation of leukemic K-562 cells.
    Respinomycin A2
  • HY-N15050
    Cervicarcin
    Inhibitor
    Cervicarcin is an antitumor antibiotic with a strong inhibitory effect on sarcoma 180 and sarcoma NF, but has a weak effect on sarcoma 37, Ehrman's ascites cancer and Friend leukemia.
    Cervicarcin
  • HY-176776
    Antibacterial agent 287
    Inhibitor
    Antibacterial agent 287 (Compound 26), a derivative of Deoxynybomycin (HY-116926), is an antibacterial agent. Antibacterial agent 287 has potent antibacterial activity against a variety of Gram-negative bacterium with MICs of 0.5, 0.5 and 0.06 μg/mL for WT S. aureus, WT E. coli and E. coli ΔtolC, respectively. Antibacterial agent 287 can be used for multidrug-resistant (MDR) bacterium infections research.
    Antibacterial agent 287
  • HY-178019
    NDM-1-IN-10
    Inhibitor
    NDM-1-IN-10 (Compound CS-23) is an irreversible and covalent New Delhi metallo-β-lactamase-1 (NDM-1) inhibitor with an IC50 of 36  nM. NDM-1-IN-10 shows a synergistic effect with Meropenem (HY-13678) against NDM-1-expressing E. coli ( MIC of 0.25 μg/mL for E. coli BL21/pET15b-blaNDM-1). NDM-1-IN-10 can be used for bacterial infections research.
    NDM-1-IN-10
  • HY-N13221
    Apple Cider Vinegar Powder
    Inhibitor
    Apple Cider Vinegar Powder is a soluble powdered form of apple cider vinegar. Apple Cider Vinegar Powder has anti-bacterial, anti-oxidant, and antibiotic properties and can help maintain the acid-base balance in the blood. Apple Cider Vinegar Powder can lower blood sugar and lipid levels. Apple Cider Vinegar Powder is used in research related to tumors, diabetes, and cardiovascular diseases.
    Apple Cider Vinegar Powder
  • HY-N14255
    Memnobotrin A
    Inhibitor
    Memnobotrin A is an antibiotic found in Memnoniella echinata (JS6308). Memnobotrin A has inhibitory effect on NCI-460, MCF7 and SF-268 cell lines.
    Memnobotrin A
  • HY-115846
    ML370
    Inhibitor
    ML370 is an antibacterial agent. ML370 exerts antibacterial activity by inhibiting the activity of Vibrio cholerae LuxO kinase. ML370 can be used in the research of infectious diseases such as cholera.
    ML370
  • HY-N5188
    Emerimicin III
    Inhibitor
    Emerimicin III mainly has activity against Gram-positive bacteria.
    Emerimicin III
  • HY-N14644
    Hazimycin 5
    Inhibitor
    Hazimycin 5 has weak activity against Gram-negative bacteria, yeast and skin fungi.
    Hazimycin 5
  • HY-168900
    Antibiofilm agent-16
    Inhibitor
    Antibiofilm agent-15 (Compound 17) is an antibacterial agent. Antibiofilm agent-15 inhibits biofilm formation in Gram-positive and Gram-negative bacteria.
    Antibiofilm agent-16
  • HY-N14460
    Pluracidomycin C3
    Inhibitor
    Pluracidomycin C3 is a carbapenem antibiotic. Pluracidomycin C3 has anti-Gram-positive bacteria and Gram-negative bacteria activities.
    Pluracidomycin C3
  • HY-N14702
    2-Hydroxygentamicin B
    Inhibitor
    2-Hydroxygentamicin B is a 3 aminoglycoside antibiotic with anti-Gram-positive and negative bacteria activity.
    2-Hydroxygentamicin B
Cat. No. Product Name / Synonyms Application Reactivity