2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

Related Products

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N2094R
    Genipin 1-β-D-gentiobioside (Standard) 29307-60-6
    Genipin 1-β-D-gentiobioside (Genipin 1-gentiobioside) is one of the most abundant and bioactive iridoid glycosides in Gardenia jasminoides Ellis, which possesses hepatoprotective, anti-inflammatory, antioxidant, and antithrombotic activities.
    Genipin 1-β-D-gentiobioside (Standard)
  • HY-N2106R
    Dehydroevodiamine (Standard) 67909-49-3
    Dehydroevodiamine is a major bioactive quinazoline alkaloid isolated from Evodiae Fructus, has an antiarrhythmic effect in guinea-pig ventricular myocytes. Dehydroevodiamine inhibits LPS-induced iNOS, COX-2, prostaglandin E2 (PGE2) and nuclear factor-kappa B (NF-κB) expression in murine macrophage cells.
    Dehydroevodiamine (Standard)
  • HY-N2110R
    Phellopterin (Standard) 2543-94-4
    Phellopterin (Standard) is the analytical standard of Phellopterin. Phellopterin, an orally active furocoumarin with multiple biological activities. Phellopterin is a partial agonist of the central benzodiazepine receptors. Phellopterin exerts anti-inflammatory effects by upregulating SIRT1, downregulating ICAM-1 (reducing chronic inflammation, aiding diabetic ulcer healing), inhibiting STAT3 phosphorylation (easing atopic dermatitis inflammation), regulating Akt/PKC pathways (lowering TNF-α-induced VCAM-1 to block monocyte adhesion), and inhibiting TLR4/NF-κB pathway and macrophage M2 polarization (alleviating colitis-related cancers). Phellopterin suppresses ovarian cancer progression via inhibiting the PU.1/CLEC5A/PI3K-AKT loop (inducing cell cycle arrest, apoptosis, DNA damage). Phellopterin alleviates murine diabetes by promoting adipocyte differentiation and increasing PPARγ. Phellopterin also has anti-HSV-1 activity. Phellopterin can be used for studying anti-inflammation, anti-cancer (e.g., ovarian cancer, colitis cancer), blood glucose lowering, anti-diabetes, and anti-virus.
    Phellopterin (Standard)
  • HY-N2115R
    Araloside A (Standard) 7518-22-1
    Araloside A (Standard) (Chikusetsusaponin IV (Standard)), triterpenoid saponins, is an orally active component of Aralia elata. Araloside A (Standard) shows low-renin-inhibitory activity with an IC50 of 77.4 μM. Araloside A (Standard) can inhibit cell proliferation and induce apoptosis. Araloside A (Standard) suppresses inflammatory cytokines IL-1β and IL-6 production. Araloside A (Standard) can be used for the researches of cancer, inflammation and cardiovascular disease, such as renal cell carcinoma and rheumatoid arthritis.
    Araloside A (Standard)
  • HY-N2119R
    Sciadopitysin (Standard) 521-34-6
    Sciadopitysin (Standard) is the analytical standard of Sciadopitysin. This product is intended for research and analytical applications. Sciadopitysin is a type of biflavonoids in leaves from ginkgo biloba. Sciadopitysi inhibits RANKL-induced osteoclastogenesis and bone loss by inhibiting NF-κB activation and reducing the expression of c-Fos and NFATc1.
    Sciadopitysin (Standard)
  • HY-N2123R
    Neoliquiritin (Standard) 5088-75-5
    Neoliquiritin (Standard) is the analytical standard of Neoliquiritin. This product is intended for research and analytical applications. Neoliquiritin is isolated from Glycyrrhiza uralensis with an anti-inflammatory activity.
    Neoliquiritin (Standard)
  • HY-N2144R
    7,4'-Di-O-methylapigenin (Standard) 5128-44-9
    7,4'-Di-O-methylapigenin (Standard) is the analytical standard of 7,4'-Di-O-methylapigenin. This product is intended for research and analytical applications.
    7,4'-Di-O-methylapigenin (Standard)
  • HY-N2149R
    Tomatidine (Standard) 77-59-8
    Tomatidine acts as an anti-inflammatory agent by blocking NF-κB and JNK signaling. Tomatidine activates autophagy either in mammal cells or C elegans.
    Tomatidine (Standard)
  • HY-N2151R
    Rhodojaponin II (Standard) 26116-89-2
    Rhodojaponin II (Standard) is the analytical standard of Rhodojaponin II. This product is intended for research and analytical applications. Rhodojaponin II is a diterpenoid from the leaves of Rhododendron molle with anti-inflammatory activity.
    Rhodojaponin II (Standard)
  • HY-N2156R
    Paeonolide (Standard) 72520-92-4
    Paeonolide (Standard) is the analytical standard of Paeonolide. This product is intended for research and analytical applications. Paeonolide is a plant glycoside that contains a non-reducing end α-l-arabinopyranoside and is found in the roots of the widespread plant genus Paeonia.
    Paeonolide (Standard)
  • HY-N2179R
    Hypaphorine (Standard) 487-58-1
    Hypaphorine is an indole found in Caragana korshinskii. Hypaphorine has neurological and glucose-lowering effects. Hypaphorine prevents Lipopolysaccharides (LPS) (HY-D1056)-mediated acute lung injury (ALI) and proinflammatory response via inactivating the p38/JNK signaling pathway by upregulating DUSP1.
    Hypaphorine (Standard)
  • HY-N2182R
    Episyringaresinol 4'-O-β-D-glncopyranoside (Standard) 137038-13-2
    Episyringaresinol 4'-O-β-D-glncopyranoside (Standard) is the analytical standard of Episyringaresinol 4'-O-β-D-glncopyranoside. This product is intended for research and analytical applications. Episyringaresinol 4'-O-β-D-glncopyranoside (compound 22), isolated from Alhagi sparsifolia Shap, is a natural potential neuroinflammatory inhibitor.
    Episyringaresinol 4'-O-β-D-glncopyranoside (Standard)
  • HY-N2185R
    (5R,6E)-5-Hydroxy-1,7-diphenyl-6-hepten-3-one (Standard) 87095-74-7
    (5R,6E)-5-Hydroxy-1,7-diphenyl-6-hepten-3-one (Standard) is the analytical standard of (5R,6E)-5-Hydroxy-1,7-diphenyl-6-hepten-3-one. This product is intended for research and analytical applications. (5R,6E)-5-Hydroxy-1,7-diphenyl-6-hepten-3-one is the methylene chloride extract of Alpinia nutans, has antioxidant activity.
    (5R,6E)-5-Hydroxy-1,7-diphenyl-6-hepten-3-one (Standard)
  • HY-N2192R
    Swertianolin (Standard) 23445-00-3
    Swertianolin (Standard) is the analytical standard of Swertianolin (HY-N2192). This product is intended for research and analytical applications. Swertianolin is a xanthone glycoside. Swertianolin can be isolated from plants of the Gentianaceae family (e.g., Gentiana campestris and Swertia punicea). Swertianolin inhibits p38 phosphorylation and NF-κB activation, and reduces NO and ROS production. Swertianolin exhibits anti-Helicobacter pylori activity with an IC50 of 6.1 μM and a minimum bactericidal concentration of 91.7 μM. Swertianolin modulates immune function in sepsis. Swertianolin is useful in the research of diseases such as Alzheimer's disease, hepatitis B, Helicobacter pylori infection, and sepsis.
    Swertianolin (Standard)
  • HY-N2243R
    Hosenkoside K (Standard) 160896-49-1
    Hosenkoside K (Standard) is the analytical standard of Hosenkoside K. This product is intended for research and analytical applications. Hosenkoside K is a baccharane glycoside isolated from the seeds of impatiens balsamina.
    Hosenkoside K (Standard)
  • HY-N2249R
    Hosenkoside A (Standard) 156791-82-1
    Hosenkoside A (Standard) is the analytical standard of Hosenkoside A. This product is intended for research and analytical applications. Hosenkoside A is a baccharane glycoside isolated from the seeds of impatiens balsamina.
    Hosenkoside A (Standard)
  • HY-N2250R
    Hosenkoside B (Standard) 156764-82-8
    Hosenkoside B (Standard) is the analytical standard of Hosenkoside B. This product is intended for research and analytical applications. Hosenkoside B is a baccharane glycoside isolated from the seeds of impatiens balsamina.
    Hosenkoside B (Standard)
  • HY-N2258R
    Poncirin (Standard) 14941-08-3
    Poncirin (Standard) is the analytical standard of Poncirin. This product is intended for research and analytical applications. Poncirin is isolated from Poncirus trifoliata with anti-inflammory activites. Poncirin significantly reduces mechanical hyperalgesia and allodynia in Complete Freund’s Adjuvant (CFA)-induced inflammatory pain models.
    Poncirin (Standard)
  • HY-N2259R
    Curcumenol (Standard) 19431-84-6
    Curcumenol ((+)-Curcumenol) is a potent CYP3A4 inhibitor with an IC50 of 12.6 μM, which is one of constituents in the plants of medicinally important genus of Curcuma zedoaria, with neuroprotection, anti-inflammatory, anti-tumor and hepatoprotective activities. Curcumenol ((+)-Curcumenol) suppresses Akt-mediated NF-κB activation and p38 MAPK signaling pathway in LPS-stimulated BV-2 microglial cells.
    Curcumenol (Standard)
  • HY-N2344R
    Procyanidin A1 (Standard) 103883-03-0
    Procyanidin A1 (Standard) is the analytical standard of Procyanidin A1. This product is intended for research and analytical applications. Procyanidin A1 (Proanthocyanidin A1) is a procyanidin dimer, which inhibits degranulation downstream of protein kinase C activation or Ca2+ influx from an internal store in RBL-213 cells. Procyanidin A1 has antiallergic effects.
    Procyanidin A1 (Standard)
Cat. No. Product Name / Synonyms Application Reactivity