2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N15660
    Azafrin 507-61-9
    Azafrin, a carotenoid, is one of the most abundant active ingredients in C. grandiflora. Azafrin increases HO-1, NQO1, and Nrf2 expression. Azafrin shows cardioprotective effect against myocardial injury via activation of the Nrf2-ARE pathway. Azafrin can be used for research of cardiovascular diseases.
    Azafrin
  • HY-N15662
    Coumestan 479-12-9
    Coumestan is a secondary metabolite found in leguminous plants and can be used as drug intermediate Coumestan can be used to synthesize various coumarin compounds such as Coumestrol (HY-N2335), Glytabastan B, and Coumestan Pks13 inhibitor. Coumestans can be used for the study of anti-cancer, anti-inflammatory, anti-oxidative, antibacterial, neuroprotective and organ protective.
    Coumestan
  • HY-N15689
    Dichotomine E 861024-08-0
    Dichotomine E is a β-carboline alkaloid that can be isolated from the root of Stellaria dichotoma var. lanceolata. Dichotomine E has anti-inflammatory property for the inhibition of NO production in LPS (HY-D1056)-treated RAW264.7 cells.
    Dichotomine E
  • HY-N15691
    Tadehaginoside 2020004-61-7
    Tadehaginoside, a phenylpropanoid glycoside, is a regulator of lipogenesis and glucose consumption. Tadehaginoside has antioxygenic property. Tadehaginoside mediates liver protection against oxidative stress injury and inflammation by regulating Nrf2 and NF-κB signaling pathways in hepatocytes. Tadehaginoside can be used for the study of obesity and diabetes.
    Tadehaginoside
  • HY-N15693
    2-O-B-D-Glucopyranosyloxy-1,7,8-trimethoxy- 3-methylanthraquinone 1622982-60-8
    2-O-B-D-Glucopyranosyloxy-1,7,8-trimethoxy-3-methylanthraquinone can be found in the seeds of Cassia obtusifolia.
    2-O-B-D-Glucopyranosyloxy-1,7,8-trimethoxy- 3-methylanthraquinone
  • HY-N15704
    Cassiaside C2 218155-49-8
    Cassiaside C2 is a naphthopyrone with a strong antiallergic activity. Cassiaside C2 inhibits the histamine release from rat peritoneal exudate mast cells induced by antigen-antibody reaction.
    Cassiaside C2
  • HY-N15708
    Dichotomine C 755036-45-4
    Dichotomine C ((R)-(-)-Dichotomine C) is a β-carboline-type alkaloid with antiallergic effects. Dichotomine C inhibits the release of β-hexosaminidase in RBL-2H3 cells with an IC50 of 62 μM. Dichotomine C inhibits the releases of antigen-IgE-mediated TNF-α and IL-4 in RBL-2H3 cells with IC50s of 19 μM and 15 μM, respectively. Dichotomine C can be used for the study of type I allergic reactions.
    Dichotomine C
  • HY-N15710
    Magnotriol B 92829-71-5
    Magnotriol B is a cholinesterase inhibitor with IC50 values of 12.63 nM and 14.5 nM against AChE and BChE, respectively. Magnotriol B also exhibits significant NO inhibitory activity with an IC50 of 2.02 μM. Magnotriol B can be used in the research of neurodegenerative and inflammatory diseases.
    Magnotriol B
  • HY-N15711
    Ganoleucoin R 2230922-02-6
    Ganoleucoin R is a triterpenoid compound that can be isolated from Ganoderma leucocontextum. Ganoleucoin R exerts a protective effect against H2O2-induced oxidative damage and can promote neurite outgrowth in PC12 cells. Ganoleucoin R possesses neuroprotective and neurogenic activities, and can be used in the research of neurodegenerative diseases.
    Ganoleucoin R
  • HY-N15718
    Dichotomine D 755036-50-1
    Dichotomine D is a β-carboline alkaloid found in the roots of Stellaria dichotoma. Dichotomine D acts as an antiallergic agent. Dichotomine D is promising for research of type I allergic reactions.
    Dichotomine D
  • HY-N15722
    9-O-β-D-Glucopyranosyl-3,4-dimethoxy-cinnamic acid 223137-18-6
    9-O-β-D-Glucopyranosyl-3,4-dimethoxy-cinnamic acid is an orally active phenylpropanoid glycoside found in Microlepia pilosissima, acting as an antioxidant. 9-O-β-D-Glucopyranosyl-3,4-dimethoxy-cinnamic acid shows a DPPH radical scavenging activity with an ED50 value of 38.1 μM. 9-O-β-D-Glucopyranosyl-3,4-dimethoxy-cinnamic acid is promising for research of oxidative stress-related diseases such as inflammation and liver injury.
    9-O-β-D-Glucopyranosyl-3,4-dimethoxy-cinnamic acid
  • HY-N15727
    2,5-Dimethylchromone-7-O-β-D-glucopyranoside 1251459-63-8
    2,5-Dimethylchromone-7-O-β-D-glucopyranoside is an orally active chromone glycoside found in the underground parts of Rheum australe. 2,5-Dimethylchromone-7-O-β-D-glucopyranoside shows a DPPH radical scavenging activity with an IC50 value of 66.9 μM. 2,5-Dimethylchromone-7-O-β-D-glucopyranoside scavenges free radicals by providing hydrogen atoms through phenolic hydroxyl groups, inhibiting lipid peroxidation. 2,5-Dimethylchromone-7-O-β-D-glucopyranoside is promising for research of oxidative stress-related diseases such as inflammation and skin diseases.
    2,5-Dimethylchromone-7-O-β-D-glucopyranoside
  • HY-N15728
    2-(2'-Hydroxypropyl)-5-methyl-7-hydroxychromone-7-O-β-D-glucopyranoside 94356-36-2
    2-(2'-Hydroxypropyl)-5-methyl-7-hydroxychromone-7-O-β-D-glucopyranoside (Compound 5) is an orally active chromone glycoside found in the roots of Rumex patientia. 2-(2'-Hydroxypropyl)-5-methyl-7-hydroxychromone-7-O-β-D-glucopyranoside is promising for research of oxidative stress-related fields such as inflammation and metabolic diseases.
    2-(2'-Hydroxypropyl)-5-methyl-7-hydroxychromone-7-O-β-D-glucopyranoside
  • HY-N15731
    Cyanidin 3-xylosyl-(feruloyl-glucosyl)-galactoside 142354-30-1
    Cyanidin 3-xylosyl-(feruloyl-glucosyl)-galactoside (Compound 5) is an orally active cyanidin triglycoside derivative found in carrot cell suspension cultures. Cyanidin 3-xylosyl-(feruloyl-glucosyl)-galactoside is promising for research of natural pigment stability, antioxidant mechanisms, and oxidative stress-related diseases (e.g., inflammation).
    Cyanidin 3-xylosyl-(feruloyl-glucosyl)-galactoside
  • HY-N15751
    Haploperoside A 74712-71-3
    Haploperoside A (Scopolin-6'-O-α-L-rhamnopyranoside) is found in the roots of Althaea officinalis. Haploperoside A has the potential to be used in the study of oral tissue inflammation and cough.
    Haploperoside A
  • HY-N15754
    3-Hydroxy-2-methylglutaric acid 54665-33-7
    3-Hydroxy-2-methylglutaric acid is a carboxylic acid metabolite. 3-Hydroxy-2-methylglutaric acid can be isolated from the flower Veronica incana L. 3-Hydroxy-2-methylglutaric acid can be used for upper respiratory tract diseases, malignant neoplasms, gastrointestinal tract and genitourinary system disorders and diabetes mellitus research.
    3-Hydroxy-2-methylglutaric acid
  • HY-N15756
    N-Demethylsinomenine 240131-71-9
    N-Demethylsinomenine is a morphinane alkaloid that can be isolated from Sinomenium acutum. N-Demethylsinomenine has a protective effect against H2O2-induced cell injury. N-Demethylsinomenine can be used in the research of diseases such as Alzheimer's disease.
    N-Demethylsinomenine
  • HY-N15770
    VSA 2 2489675-56-9 98%
    VSA 2, a saponin-based vaccine adjuvant, is a derivative of Momordica saponin (MS) II. VSA 2 is an immunostimulant, shows consistent enhancement of immunoglobulin G2a (IgG2a) production when it was in formulation with either ovalbumin or recombinant hemagglutinin B (rHagB) antigen.
    VSA 2
  • HY-N15793
    C23 Glucosyl(β) ceramide (d18:1/23:0) 28224-95-5 98%
    C23 Glucosyl(β) ceramide (d18:1/23:0) is a β-Glucosyl ceramide.
    C23 Glucosyl(β) ceramide (d18:1/23:0)
  • HY-N15840
    C18:2 Glucosyl(ß) ceramide (d18:1/18:2) 3077426-94-6
    C18:2 Glucosyl(β) ceramide (d18:1/18:2) is a β-Glucosyl ceramide.
    C18:2 Glucosyl(ß) ceramide (d18:1/18:2)
Cat. No. Product Name / Synonyms Application Reactivity